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Updated: Dec 22, 2025

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
Published on: November 26, 2018
Collectively Answering the Venetoclax BTK Inhibitor Sequencing Question in CLL
1Division of Hematology, The Ohio State University, Columbus, Ohio. kerry.rogers@osumc.edu.
Abstract:
Whether BTK inhibitors are effective when used after venetoclax in patients with chronic lymphocytic leukemia is an important unanswered question. In a large retrospective cohort study examining outcomes for next line treatment after venetoclax, BTK inhibitors were found to result in durable responses in patients who were not previously BTK inhibitor resistant.See related article by Mato et al., p. 3589.
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