Related Experiment Video
Updated: Dec 22, 2025

Author Spotlight: Advantages of Pressure-Volume Loop Measurement Method in Cardiovascular Research
Published on: January 12, 2024
Pharmacological and Therapeutic Aspects of Plants from the Genus Ferula: A Comprehensive Review
Mohammad Sabzehzari1, Mohammad Reza Naghavi1, Motahare Bozari2
1Division of Biotechnology, Agronomy and Plant Breeding Department, University of Tehran, Tehran, Iran.
Abstract:
Inspired by nature, humankind has been able to attain significant achievements in the drug and food industries. Particularly, medicinal plants are a rich source of medicinal, cosmetic, sanitary, and aromatic substances. Genus Ferula from the Apiaceae family is a plant genus that possesses over 170 species, which have been carefully documented with regard to their medicinal properties. Ferula spp. affects many body organs, and their respective functions, in humans, such as the immune system, gastrointestinal tract, genitourinary, endocrine, respiratory, cardiovascular, nervous system, bone (skeleton), and teeth. In spite of the benefits, ferulosis (Ferula toxicity) is an important aspect of Ferula consumption in humans and animals. Hemorrhagic problems and infertility are important signs of ferulosis. In this review, we have described all of the effects of the active ingredients of Ferula spp. and their mechanisms of actions, when known, based on an extensive literature review. Thus, our review opens a window of the benefits of Ferula as a phyto-pharmaceutical and its therapeutic applications in pharmacy, dentistry, and medicine.
Related Concept Videos
Plant Hormones
Therapeutic Index
Fungal Phylum Ascomycota
Heart Failure Drugs: Inotropic Agents
Principles of Drug Action
Drugs can be agonists or antagonists. Like the endogenous ligands, agonists always bind and activate the target to produce a cellular response. Agonist binding induces a conformational change which in turn...

