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Comparative effectiveness of probiotic-based formulations on cecal microbiota modulation in broilers.

Denise R Rodrigues¹, Whitney Briggs¹, Audrey Duff¹

¹Department of Animal Sciences, The Ohio State University, Columbus, Ohio, United States of America.

|May 6, 2020

Summary

This summary is machine-generated.

Probiotic formulations varied in their ability to alter broiler cecal microbiota. While some reduced microbial diversity, only the synbiotic (SYNBIO) significantly impacted microbial community structure.

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Area of Science:

Animal Science
Microbiology
Gut Health

Background:

Probiotics can modulate the gut microbiome, potentially improving poultry health and performance.
Understanding the impact of different probiotic formulations on broiler gut microbiota is crucial for optimizing their use.

Purpose of the Study:

To evaluate the efficacy of five distinct probiotic formulations in modulating the cecal microbiota of broilers.
To assess changes in microbial diversity and community structure at 21 and 42 days of age.

Main Methods:

Analysis of alpha and beta diversity metrics (e.g., weighted and unweighted Unifrac) of cecal microbiota.
Comparison of five treatments: synbiotic (SYNBIO), yeast (YEAST), and three single-strain Bacillus formulations (SINGLE1, SINGLE2, SINGLE3) against a control (CON).
Taxonomic profiling of cecal microbial communities.

Main Results:

At 21 days, SINGLE1, SINGLE2, and YEAST treatments showed reduced alpha diversity compared to the control.
Significant differences in beta diversity were observed between SYNBIO and CON at 21 days (P = 0.02).
No significant differences in alpha or beta diversity or major taxonomic shifts were detected by 42 days across treatments.

Conclusions:

Not all tested probiotic formulations consistently modulated the broiler cecal microbiota.
The synbiotic (SYNBIO) formulation demonstrated a notable influence on cecal microbial community structure, likely due to transient variations in taxon abundance.