[Mophometric study of the mouth mucosa in leukoplakia simplex]

Examination of the leukoplakia simplex of the oral cavity localized on the buccal surface and in the bottom of the oral cavity was carried out in 11 cases using the method of stereological morphometry. It was established that: 1. Quantitative changes of the constituents of the cytoplasma coming into being during the process of the keratinization appear to be similar in both forms of the lokalization investigated; 2. these changes seem to be opposite to the process observed during the differentiation of the normal epithelium; 3. by comparing stereological, histopathological and clinical data a new form of leukoplakia simplex can be distinguished i.e. the indirect form of the metaplasia of the squamous epithelium. 4 Method of the stereological morphometry seesm to be suitable for the description of characteristic features of the keratinization.