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Updated: Dec 22, 2025

Author Spotlight: Unveiling the Polyfunctionality and Heterogeneity in Immune Responses
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Cytokine Storm Drugs Move from CAR T to COVID-19

    Cancer Discovery
    |May 7, 2020
    PubMed

    Insights

    Tocilizumab, an IL6 receptor-blocking antibody, may help manage cytokine storms in COVID-19 patients. However, preliminary randomized trial data present less clear-cut evidence regarding its effectiveness.

    Area of Science:

    • Immunology
    • Pharmacology
    • Infectious Diseases

    Background:

    • Cytokine storms are a severe complication of COVID-19.
    • Tocilizumab is an interleukin-6 (IL6) receptor antagonist.
    • Tocilizumab is approved for managing cytokine release syndrome in CAR T-cell therapy.

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