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Endotoxin Activity Assay for the Detection of Whole Blood Endotoxemia in Critically Ill Patients
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Published on: June 24, 2019

Endotoxemia in hemolytic uremic syndrome

P Coratelli1, E Buongiorno, G Passavanti

  • 1Institute of Nephrology, University of Bari, Italy.

Nephron
|January 1, 1988
PubMed

Hemolytic uremic syndrome (HUS) was diagnosed and confirmed by renal biopsy in an 18-year-old primigravida at the 13th week of pregnancy. Circulating endotoxin was detected and the endotoxemia was progressively reduced by hemodialysis (HD) performed daily from the 3rd to the 9th day of disease. Complete normalization of the renal function was observed on day 34. The authors emphasize the importance of detecting endotoxemia in HUS in order to initiate dialysis early; at the same time they also discuss the pathogenetic role of endotoxin in this disease.

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