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Coronavirus disease 2019: a clinical review

C-L Yang1, X Qiu, Y-K Zeng

  • 1Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, Guangxi Province, PR China. z450211@yeah.net.

European Review for Medical and Pharmacological Sciences
|May 7, 2020
PubMed

Insights

This review provides an overview of coronavirus disease 2019 (COVID-19), covering its viral structure, pathogenesis, diagnosis, and clinical features. It also compares COVID-19 with SARS and MERS, discussing potential treatments to aid global containment efforts.

Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Background:

  • The emergence of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 in late 2019 led to a global pandemic.
  • Rapid scientific research has been crucial for understanding and combating the spread of this novel virus.

Purpose of the Study:

  • To provide a comprehensive overview of COVID-19, including viral characteristics, pathogenesis, and clinical presentation.
  • To compare the clinical features of COVID-19 with those of SARS and MERS.
  • To discuss current research on potential therapeutic interventions for COVID-19.

Main Methods:

  • Literature review of existing scientific studies on COVID-19.
  • Comparative analysis of clinical data from COVID-19, SARS, and MERS.
  • Synthesis of current knowledge on viral structure, pathogenesis, diagnosis, and treatment.

Main Results:

  • COVID-19 shares similarities with SARS and MERS but presents distinct clinical characteristics.
  • Understanding viral structure and pathogenesis is key to developing diagnostic and therapeutic strategies.
  • Ongoing research explores various treatment alternatives for COVID-19.

Conclusions:

  • This review consolidates current knowledge on COVID-19 to support healthcare professionals and researchers.
  • Effective containment of the COVID-19 pandemic relies on continued scientific investigation and collaboration.
  • Comparative analysis with previous coronaviruses aids in understanding the unique aspects of SARS-CoV-2.

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