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Related Experiment Video

Updated: Dec 22, 2025

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4

Published on: August 21, 2017

ANCA-associated vasculitis causing nasopalatal destruction.

S Mumtaz¹, S Navaee¹, M Singh²

¹Royal Free London Foundation Trust, UK.

Annals of the Royal College of Surgeons of England

|May 7, 2020

Summary

This summary is machine-generated.

Autoimmune disorders like ANCA-associated vasculitis present diagnostic challenges. This case highlights the severe tissue destruction possible without early intervention, emphasizing the need for prompt management of these debilitating conditions.

Area of Science:

Immunology
Rheumatology
Otolaryngology

Background:

Keywords:

ANCA-associated Autoimmune disorders Otolaryngology Septal perforation Vasculitis

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Autoimmune disorders present diagnostic and management difficulties due to ambiguous and debilitating symptoms.
Delayed intervention in autoimmune conditions can lead to irreversible consequences like vision or hearing loss and tissue destruction.
Vasculitis affecting the head and neck is an uncommon but serious manifestation of systemic autoimmune disease.