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Updated: Aug 17, 2026

Implantation of the Syncardia Total Artificial Heart
Published on: July 18, 2014
Continuous-flow total artificial heart port-to-port connection technique using dedicated de-airing sleeve
Jamshid H Karimov1, Shengqiang Gao1,2, Kiyotaka Fukamachi1
1Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Abstract:
Preventing the introduction of air while a mechanical circulatory support device is being implanted is critical for successful outcomes. A substantial amount of air may be introduced into the circulation during the pump-to-outflow and/or pump-to-inflow port connection, which can be detrimental to optimal pump function and long-term survival. We have developed a novel connecting sleeve that enables an airless connection of the continuous-flow total artificial heart to the conduits. Herein, we describe the device design and surgical techniques evaluated in vivo.

