Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

COX-2 inhibition improves immune system homeostasis and decreases liver damage in septic rats.

The Journal of surgical research·2009
Same author

Mass spectral characterization of organophosphate-labeled, tyrosine-containing peptides: characteristic mass fragments and a new binding motif for organophosphates.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences·2009
Same author

3D-SURFER: software for high-throughput protein surface comparison and analysis.

Bioinformatics (Oxford, England)·2009
Same author

Total arch replacement with stented elephant trunk technique: a proposed treatment for complicated Stanford type B aortic dissection.

Journal of cardiac surgery·2009
Same author

Top-emitting white organic light-emitting devices with a one-dimensional metallic-dielectric photonic crystal anode.

Optics letters·2009
Same author

[Detection of tick and tick-borne pathogen in some ports of Inner Mongolia].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2009
Same journal

[MS-DTNet: an efficient model combining multi-scale convolution and dual-tower attention for detecting abnormal heart sounds].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University·2026
Same journal

[A bidirectional feature mapping classification model based on multi-constrained latent representation learning for differential diagnosis of pneumonia].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University·2026
Same journal

[A Transformer-based multimodal model for predicting hospital-acquired infections using imaging and clinical laboratory data].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University·2026
Same journal

[Image-guided application of plant pigment patch and laser microdot ablation for surface marking in radiotherapy for breast cancer: a randomized controlled trial].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University·2026
Same journal

[Serum from rats with electroacupuncture activates the PI3K/Akt signaling pathway to improve synaptic plasticity in HT22 neurons with oxygen and glucose deprivation].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University·2026
Same journal

[Impact of HIV-1 genotypes and population mobility on HIV-1 transmission in Guangzhou: a molecular transmission network analysis].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University·2026
See all related articles

Related Experiment Video

Updated: Dec 22, 2025

Extracellular Vesicle Uptake Assay via Confocal Microscope Imaging Analysis
08:32

Extracellular Vesicle Uptake Assay via Confocal Microscope Imaging Analysis

Published on: February 14, 2022

8.8K

[Progress in extracellular vesicle imaging methods].

Kaizhe Wang1,2, Yuhui Wei1,3, Ping Zhang1,2

  • 1CAS Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China.

Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University
|May 8, 2020
PubMed
Summary
This summary is machine-generated.

Extracellular vesicles (EVs) are crucial for cell communication. This review details EV imaging techniques, highlighting challenges and future directions for single-vesicle and single-cell studies.

Keywords:
exosomesextracellular vesiclesimagingmicrovesicles

More Related Videos

Rapid Fluorescence-based Characterization of Single Extracellular Vesicles in Human Blood with Nanoparticle-tracking Analysis
09:16

Rapid Fluorescence-based Characterization of Single Extracellular Vesicles in Human Blood with Nanoparticle-tracking Analysis

Published on: January 7, 2019

10.2K
Direct Stochastic Optical Reconstruction Microscopy of Extracellular Vesicles in Three Dimensions
09:36

Direct Stochastic Optical Reconstruction Microscopy of Extracellular Vesicles in Three Dimensions

Published on: August 26, 2021

4.3K

Related Experiment Videos

Last Updated: Dec 22, 2025

Extracellular Vesicle Uptake Assay via Confocal Microscope Imaging Analysis
08:32

Extracellular Vesicle Uptake Assay via Confocal Microscope Imaging Analysis

Published on: February 14, 2022

8.8K
Rapid Fluorescence-based Characterization of Single Extracellular Vesicles in Human Blood with Nanoparticle-tracking Analysis
09:16

Rapid Fluorescence-based Characterization of Single Extracellular Vesicles in Human Blood with Nanoparticle-tracking Analysis

Published on: January 7, 2019

10.2K
Direct Stochastic Optical Reconstruction Microscopy of Extracellular Vesicles in Three Dimensions
09:36

Direct Stochastic Optical Reconstruction Microscopy of Extracellular Vesicles in Three Dimensions

Published on: August 26, 2021

4.3K

Area of Science:

  • Biotechnology
  • Cell Biology
  • Nanotechnology

Background:

  • Extracellular vesicles (EVs), including exosomes and microvesicles, are key mediators of intercellular communication.
  • EVs transfer proteins, mRNA, miRNA, and lipids, influencing physiological and pathological processes.
  • The small size and heterogeneity of EVs present challenges in characterizing their functions.

Purpose of the Study:

  • To provide a comprehensive overview of extracellular vesicle (EV) imaging methods.
  • To discuss strategies for EV origin, separation, and dynamic tracking.
  • To analyze the advantages and disadvantages of various EV imaging techniques.

Main Methods:

  • Review of established and emerging EV visualization and imaging methodologies.
  • Analysis of techniques for tracking EVs from their origin to their interactions.
  • Discussion of methods applicable to single EV and single-cell analyses.

Main Results:

  • Various imaging methods exist for studying EV characteristics and roles.
  • Challenges in EV identification stem from their nanoscale size and heterogeneity.
  • Different imaging strategies offer distinct advantages and limitations.

Conclusions:

  • Understanding EV imaging is critical for deciphering their biological roles.
  • Future research frontiers lie in single-vesicle and single-cell imaging of EVs.
  • Advanced imaging techniques are essential for overcoming current characterization limitations.