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Updated: Dec 22, 2025

Measuring Cardiac Autonomic Nervous System ANS Activity in Children
Published on: April 29, 2013
Assessment of Autonomic Nervous System in Children with Celiac Disease: A Heart Rate Variability Study
1Department of Pediatric Cardiology, Health Sciences University, Kecioren Training and Research Hospital, Ankara, Turkey. Correspondence to: Dr Seyma Kayali, Department of Pediatric Cardiology, Kecioren Training and Research Hospital, Pýnarbasi Mah, Sanatoryum Cad, Ardahan Sok No.25, 06380 Kecioren, Ankara. ak-seyma@hotmail.com.
Objective:
We evaluated the activity of autonomic nervous system in children with celiac disease by using heart rate variability (HRV) analysis.
Methods:
HRV parameters of 37 children with celiac disease were compared to 36 age- and sex-matched healthy controls. None of the participants had a systemic, central or peripheral neurological disease.
Results:
Statistically significant differences were present in two parameters; standard deviation of all RR intervals (SDNN) and standard deviation of 5-minute RR interval means (SDANN). Age was negatively correlated with mean, minimum and maximum heart rate. Duration of disease was positively correlated with low frequency power-high frequency power ratio. No correlation was found between anti-tissue transglutaminase IgA level and HRV parameters.
Conclusions:
Celiac disease may affect autonomic nervous function in children even if there are no symptoms of dysautonomia.
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