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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
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NON-FUNCTIONAL PITUITARY TUMORS: A MISLEADING PRESENTATION OF AN INTRASELLAR PLASMACYTOMA
R Pujia1, D Russo2, E Guadagno2
1"Magna Græcia" University of Catanzaro, Dept. of Health Sciences, Catanzaro, Catanzaro, Italy.
Acta Endocrinologica (Bucharest, Romania : 2005)
|May 8, 2020
Summary
Intrasellar plasmacytoma, a rare pituitary tumor, was diagnosed in a 77-year-old woman. Early consideration in pituitary mass differentials is crucial due to its distinct treatment and potential progression to multiple myeloma.
Area of Science:
- Endocrinology
- Oncology
- Neurosurgery
Background:
- Intrasellar plasmacytoma is an exceptionally rare pituitary tumor originating from monoclonal plasma cells.
- Current understanding relies solely on isolated case reports, highlighting a significant knowledge gap.
Observation:
- A 77-year-old woman presented with a presumptive diagnosis of non-functioning pituitary adenoma based on clinical and radiological findings.
- Endoscopic endonasal transsphenoidal surgery was performed for the sellar mass.
Findings:
- Immunohistochemical analysis of the resected sellar mass confirmed the definitive diagnosis of intrasellar plasmacytoma.
- This rare tumor requires careful evaluation within the differential diagnosis of pituitary masses.
Implications:
- Intrasellar plasmacytoma necessitates a distinct therapeutic strategy and carries a different prognosis compared to pituitary adenomas.
- Prompt diagnosis is vital as intrasellar plasmacytoma has a propensity for progression to multiple myeloma.
