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Synthesis and antimicrobial activity of some N-monosubstituted 2-(2-aminothiazol-4-yl)-(Z)-2-methoxyiminoacetamides
L Garuti1, A Ferranti, L Varoli
1Department of Pharmaceutical Science, University of Fermentation Chemistry, Faculty of Pharmacy, Bologna, Italy.
Die Pharmazie
|August 1, 1988
Abstract:
A short series of N-monosubstituted (aryl, aminoacyl, dipeptidyl)-2-(2-aminothiazol-4-yl)-(Z) -2-methoxyiminoacetamides was synthesized and tested for antimicrobial activity. A few members showed a somewhat interesting inhibitory action against Cryptococcus neoformans (MIC = 150 micrograms/ml).