Multiple Sclerosis in sub-Saharan Africa - a scoping review

Area of Science:

• Neurology
• Public Health
• Epidemiology

Background:

• Limited research exists on Multiple Sclerosis (MS) in sub-Saharan Africa.
• Understanding the MS landscape in this region is crucial for improving patient outcomes.
• This review synthesizes existing studies to provide regional insights.

Purpose of the Study:

• To synthesize original studies on Multiple Sclerosis (MS) from sub-Saharan Africa.
• To enhance the understanding of the academic and health landscape of MS in the region.
• To provide a historical context for MS research in sub-Saharan Africa.

Main Methods:

• A comprehensive scoping review of original research was performed.
• Databases searched included PubMed, SCOPUS, Web of Science, and EBSCO host.
• A narrative synthesis approach was employed to analyze the findings.

Main Results:

• Thirty-one unique studies from sub-Saharan Africa were identified.
• The majority of studies originated from South Africa (77%).
• Most studies focused on MS epidemiology and risk factors, with no randomized clinical trials found.

Conclusions:

• MS research in sub-Saharan Africa, though scarce, aligns with international trends.
• There is a significant need for studies on MS patient care and management in an African context.
• Increasing MS prevalence and the noncommunicable disease epidemic highlight the urgency for regional research.