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Bisphenol A in infant urine and baby-food samples among 9- to 15-month-olds

Jangwoo Lee1, Young-Ah Ahn1, Kyungho Choi1

  • 1School of Public Health, Seoul National University, Seoul, Republic of Korea.

The Science of the Total Environment
|May 9, 2020
PubMed

Insights

This study measured bisphenol A (BPA) in infant food and urine, finding BPA in most samples. Despite increasing food BPA with age, infant urine BPA levels remained consistent, suggesting other exposure sources.

Area of Science:

  • Environmental Health
  • Pediatric Nutrition
  • Toxicology

Background:

  • Diet is the primary source of bisphenol A (BPA) exposure.
  • Limited data exist on BPA levels in the diet of infants under two years old.
  • Understanding infant exposure is crucial due to potential health impacts.

Purpose of the Study:

  • To investigate BPA levels in homemade baby food and infant urine.
  • To assess BPA exposure in Korean infants aged 9, 12, and 15 months.
  • To explore the relationship between dietary BPA intake and urinary BPA levels in young children.

Main Methods:

  • Collected homemade baby food (n=210) and urine (n=187) samples from 173 Korean infants.
  • Measured BPA in food using Gas Chromatography-Mass Spectrometry (GC-MS).
  • Measured BPA in urine using High-Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS).

Main Results:

  • BPA was detected in 85.5-85.7% of urine samples and 32.5-76.3% of food samples.
  • Median BPA levels were 0.45 ng/g in food and 0.93-0.94 μg/L in urine.
  • While BPA in food increased significantly with age (especially at 15 months), urinary BPA levels did not differ significantly by infant age.

Conclusions:

  • Detected BPA levels were comparable to or lower than previous studies.
  • The lack of increase in urinary BPA with age suggests that solid food, even with higher water content, may not be the primary driver of internal dose in younger infants.
  • Other sources of BPA exposure in baby food and the environment warrant further investigation.

Keywords:
Baby-foodBisphenol AExposureInfantUrine

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