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Cardiovascular system and COVID-19: perspectives from a developing country
Shekhar Kunal1, Kashish Gupta2, Shashi Mohan Sharma3
1Department of Cardiology, Sawai Man Singh Medical College, Jaipur. shekhar.kunal09@gmail.com.
Insights
The novel coronavirus (SARS-CoV-2) causes COVID-19, frequently affecting the respiratory system but also leading to cardiovascular complications. Further research is needed to understand the link between the virus and heart conditions, especially in developing nations.
Area of Science:
- Infectious Diseases
- Cardiology
- Public Health
Background:
- The emergence of SARS-CoV-2, the virus responsible for COVID-19, has led to a global pandemic.
- COVID-19 primarily affects the respiratory system but is increasingly recognized for its cardiovascular implications.
Purpose of the Study:
- To review the cardiovascular manifestations of COVID-19.
- To discuss the impact of cardiovascular co-morbidities on COVID-19 prognosis.
- To highlight the challenges in cardiovascular care delivery in developing countries during the pandemic.
Main Methods:
- Literature review of existing studies on COVID-19 and cardiovascular involvement.
- Analysis of reported complications such as acute cardiac injury, heart failure, and arrhythmias.
- Discussion of potential mechanisms linking SARS-CoV-2 to cardiovascular disease.
Main Results:
- Cardiovascular complications are common in severe COVID-19 cases.
- Pre-existing cardiovascular conditions like hypertension worsen COVID-19 outcomes.
- The exact mechanisms of cardiac involvement by SARS-CoV-2 require further investigation.
Conclusions:
- COVID-19 poses a significant threat to cardiovascular health globally.
- The pandemic exacerbates challenges in managing cardiovascular diseases, particularly in resource-limited settings.
- Integrated research is crucial to understand and mitigate the cardiovascular impact of COVID-19.
Abstract:
A novel coronavirus, SARS-CoV-2, thought to have originated from bats causes COVID-19 infection which was first reported from Wuhan, China in December 2019. This virus has a high infectivity rate and has impacted a significant chunk of the population worldwide. The spectrum of disease ranges from mild to severe with respiratory system being the most commonly affected. Cardiovascular system often gets involved in later stages of the disease with acute cardiac injury, heart failure and arrhythmias being the common complications. In addition, the presence of cardiovascular co-morbidities such as hypertension, coronary artery disease in these patients are often associated with poor prognosis. It is still not clear regarding the exact mechanism explaining cardiovascular system involvement in COVID-19. Multiple theories have been put forward however, more robust studies are required to fully elucidate the "heart and virus" link. The disease has already made its presence felt on the global stage and its impact in the developing countries is going to be profound. These nations not only have a poorly developed healthcare system but there is also a huge burden of cardiovascular diseases. As a result, COVID-19 would adversely impact the already overburdened healthcare network leading to impaired cardiovascular care delivery especially for acute coronary syndrome and heart failure patients.
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