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COVID-19 Testing, Epidemic Features, Hospital Outcomes, and Household Prevalence, New York State-March 2020
Eli S Rosenberg1, Elizabeth M Dufort2, Debra S Blog2
1University at Albany School of Public Health, State University of New York, Rensselaer, New York, USA.
Insights
In March 2020, New York State experienced a significant COVID-19 outbreak. Early cases showed high household infection rates, with increasing risks of hospitalization and death by month
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- New York State became the epicenter of the US coronavirus disease 2019 (COVID-19) epidemic in March 2020.
- The epidemic was characterized by substantial hospitalizations and mortality.
- This study focuses on testing, risk factors, outcomes, and household prevalence during the initial phase of the outbreak in New York State.
Purpose of the Study:
- To report the extent of COVID-19 testing and test results in New York State during March 2020.
- To identify risk factors and outcomes associated with COVID-19.
- To determine household prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among initial cases.
Main Methods:
- COVID-19 testing was performed in healthcare settings, community sites, and via home testing.
- Data on demographics, risk factors, and hospital outcomes were collected through epidemiological investigations and electronic medical records.
- Household prevalence was estimated by testing household members of initial COVID-19 cases.
Main Results:
- In March 2020, New York State reported 47,326 positive COVID-19 cases out of 141,495 tests (33% positivity rate), with the highest concentration in metropolitan counties.
- Among 229 initial cases diagnosed by March 12, 13% were hospitalized and 2% died by March 30.
- Testing of 498 household members revealed a 57% infection rate (38% excluding first-reported cases), with a significant age gradient in prevalence (23% in <5 years to 68% in ≥65 years).
Conclusions:
- New York State experienced a substantial and escalating COVID-19 outbreak in March 2020.
- Early COVID-19 cases demonstrated high household infection rates.
- By the end of March, the risks of hospitalization and mortality associated with COVID-19 were significant.
Background:
The US' coronavirus disease 2019 (COVID-19) epidemic has grown extensively since February 2020, with substantial associated hospitalizations and mortality; New York State has emerged as the national epicenter. We report on the extent of testing and test results during the month of March in New York State, along with risk factors, outcomes, and household prevalence among initial cases subject to in-depth investigations.
Methods:
Specimen collection for COVID-19 testing was conducted in healthcare settings, community-based collection sites, and by home testing teams. Information on demographics, risk factors, and hospital outcomes of cases was obtained through epidemiological investigations and an electronic medical records match, and summarized descriptively. Active testing of initial case's households enabled estimation of household prevalence.
Results:
During March in New York State, outside of New York City, a total of 47 326 persons tested positive for severe acute respiratory syndrome coronavirus 2, out of 141 495 tests (33% test-positive), with the highest number of cases located in the metropolitan region counties. Among 229 initial cases diagnosed through 12 March, by 30 March 13% were hospitalized and 2% died. Testing conducted among 498 members of these case's households found prevalent infection among 57%, excluding first-reported cases 38%. In these homes, we found a significant age gradient in prevalence, from 23% among those < 5 years to 68% among those ≥ 65 years (P < .0001).
Conclusions:
New York State faced a substantial and increasing COVID-19 outbreak during March 2020. The earliest cases had high levels of infection in their households and by the end of the month, the risks of hospitalization and death were high.
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