Related Experiment Videos
[Anterior uveitis in ankylosing spondylitis. A retrospective study]
G Piergiacomi1, M Agostinelli, V Baccarini
1Université d'Ancône, Cattedra di Reumatologia, Facoltà di Medicina, Italie.
Revue Du Rhumatisme Et Des Maladies Osteo-Articulaires
|December 1, 1988
Summary
Anterior uveitis (AUV) affects 8.3% of hospitalized ankylosing spondylitis (AS) patients, with lower incidence in Italian populations. This eye condition can sometimes precede joint symptoms in AS disease progression.
Area of Science:
- Ophthalmology and Rheumatology
- Clinical Epidemiology
Context:
- Ankylosing spondylitis (AS) is a chronic inflammatory disease primarily affecting the spine.
- Anterior uveitis (AUV) is a known extra-articular manifestation of AS, but its prevalence varies across populations.
Purpose:
- To determine the prevalence of anterior uveitis (AUV) in a cohort of hospitalized patients with ankylosing spondylitis (AS).
- To compare the observed AUV incidence in Italian AS patients with international data.
- To investigate AUV as a potential initial manifestation of AS.
Summary:
- A review of 338 hospitalized AS patients identified AUV in 8.3% (7.7% males, 14.8% females).
- In 0.9% of cases, AUV preceded joint involvement, suggesting it can be an early sign of AS.
- The study found a lower AUV incidence in Italian AS patients compared to other European and global series, potentially due to genetic factors or underdiagnosis.
Impact:
- Highlights the importance of ophthalmic screening in AS patients, particularly in identifying early or undiagnosed AUV.
- Suggests potential geographical or ethnic variations in AS-associated AUV prevalence.
- Contributes to understanding the diverse clinical spectrum of ankylosing spondylitis and its extra-articular manifestations.