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Pharmacologically induced erection in patients with multiple sclerosis
H J Kirkeby1, T Petersen, E U Poulsen
1Department of Urology, Aarhus Kommunehospital, Denmark.
Scandinavian Journal of Urology and Nephrology
|January 1, 1988
Summary
Intracavernous papaverine injections effectively treated erectile dysfunction in multiple sclerosis patients. Most patients achieved rigidity, though long-term side effects require further study before routine use.
Area of Science:
- Urology
- Neurology
Background:
- Erectile dysfunction (ED) is a common complication in patients with multiple sclerosis (MS).
- Intracavernous injections offer a potential treatment for ED.
Purpose of the Study:
- To evaluate the efficacy and safety of self-administered intracavernous papaverine injections for treating ED in men with MS.
Main Methods:
- Twenty-nine male patients with MS and ED received papaverine injections.
- Treatment outcomes, including rigidity, duration, and side effects, were monitored over a mean of 8.5 months.
Main Results:
- Twenty-seven of 29 patients achieved acceptable penile rigidity.
- 92% of 297 injections resulted in rigidity lasting 8-480 minutes.
- Common side effects included minor hematomas (16 cases); two patients developed penile indurations.
Conclusions:
- Self-injection with papaverine is a safe and well-accepted treatment for ED in MS patients.
- Further research is needed to fully understand long-term side effects before routine implementation.