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Survivre et vivre: When iNKT cells met a Hippo
Luc Van Kaer1, Sebastian Joyce1,2
1Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN.
The Journal of Experimental Medicine
|May 9, 2020
Abstract
None:
Invariant natural killer T (iNKT) cells are innate-like lymphocytes with unique signaling requirements for their development and differentiation. In this issue of JEM, Raynor et al. (https://doi.org/10.1084/jem.20191157) report that the Hippo signaling pathway controls the maturation and effector differentiation of iNKT cells by modulating cellular metabolism.

