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Updated: Jul 28, 2026

Anterior Cervical Discectomy and Fusion in the Ovine Model
Published on: October 5, 2009
Total disc replacement compared with fusion for cervical degenerative disc disease: A systematic review of
Shuchao Zhai1, Aimin Li, Xiang Li
1Department of Orthopedics, Tianjin Fifth Central Hospital, Tianjin, China.
Study Design:
The present study was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement.
Objective:
The present study aimed to conduct a systematic review of overlapping meta-analyses comparing ACDR with fusion for treating CDDD in order to assist decision makers in their selection among conflicting meta-analyses and to provide treatment recommendations based on the best available evidence.
Summary Of Background Data:
Although several meta-analyses have been performed to compare total disc replacement (TDR) and fusion for treating cervical degenerative disc disease (CDDD), their findings are inconsistent.
Methods:
Multiple databases were comprehensively searched for meta-analyses comparing TDR with fusion for treating CDDD. The meta-analyses that comprised only randomized controlled trials (RCTs) were included. Two authors independently assessed the meta-analysis study quality and extracted the data. The Jadad decision algorithm was used to ascertain which meta-analysis studies represented the best evidence.
Results:
A total of 14 meta-analysis studies were included. All these studies only included RCTs and were determined as Level-II evidence.
Conclusions:
Cervical disc arthroplasty was superior compared to anterior discectomy and fusion for the treatment of symptomatic cervical disc disease.
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