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ECG Indices Poorly Predict Left Ventricular Hypertrophy and Are Applicable Only in Individuals With Low

Małgorzata Chlabicz1,2, Jacek Jamiołkowski1, Marlena Paniczko1

  • 1Department of Population Medicine and Civilization Diseases Prevention, Medical University of Bialystok, 15-269 Bialystok, Poland.

Journal of Clinical Medicine
|May 10, 2020
PubMed

Insights

Electrocardiography (ECG) has limited accuracy in detecting left ventricular hypertrophy (LVH), a key cardiovascular risk factor. New diagnostic methods are needed for better risk assessment and treatment.

Area of Science:

  • Cardiology
  • Diagnostic Imaging
  • Preventive Medicine

Background:

  • Left ventricular hypertrophy (LVH) is a significant risk factor for cardiovascular events.
  • Electrocardiography (ECG) is widely used for LVH detection despite its low sensitivity.

Purpose of the Study:

  • To assess the diagnostic performance of established ECG indicators for identifying LVH across varying cardiovascular risk levels.
  • To explore novel diagnostic approaches for LVH in the general population.

Main Methods:

  • A study involving 676 volunteers was conducted.
  • Echocardiography was used as the gold standard for LVH diagnosis.
  • Receiver operating characteristic (ROC) curve analysis was employed to evaluate ECG index efficacy.

Main Results:

  • 10.2% of participants had LVH; associated factors included older age, higher BMI, elevated blood pressure, and insulin resistance.
  • QRS duration, left atrial volume index, troponin T, and hemoglobin A1c were independently linked to LVH.
  • Sokolow-Lyon index showed no significant predictive ability; Cornell and Lewis indices had modest predictive value in certain groups.

Conclusions:

  • Current ECG methods demonstrate limited efficacy in diagnosing LVH across diverse cardiovascular risk strata.
  • There is a critical need for developing novel, simple diagnostic tools for LVH detection in the general population.
  • Improved LVH diagnosis is essential for accurate cardiovascular risk stratification and timely intervention.

Keywords:
android-type obesitycardiovascular riskelectrocardiographyleft ventricular hypertrophypopulation studies

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