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Cardiac surgery in patients with Hemophilia:is it safe?

Amjad Shalabi1,2,3,4, Erez Kachel5,6,7, Alexander Kogan5

  • 1Chaim Sheba Medical Center, Tel-Hashomer, 52621, Ramat-Gan, Israel. amjadra3008@gmail.com.

Journal of Cardiothoracic Surgery
|May 10, 2020
PubMed

Insights

Major cardiac surgery is safe for hemophilia patients with careful management. This study highlights the need for a multidisciplinary team and close monitoring for successful outcomes in hemophilia patients undergoing cardiovascular procedures.

Area of Science:

  • Cardiology
  • Hematology

Background:

  • Increased life expectancy in hemophiliacs leads to higher rates of age-related cardiovascular diseases.
  • Hemophilia patients now face similar cardiovascular disease burdens as the general population.
  • This study examines cardiac surgery outcomes in hemophiliacs.

Purpose of the Study:

  • To evaluate the safety and outcomes of cardiac surgery in patients with hemophilia.
  • To describe the peri-operative management and complications in this patient cohort.

Main Methods:

  • Retrospective review of hemophilia patients who underwent cardiac surgery between 2004 and 2019.
  • Data collected included patient demographics, hemophilia type, surgical procedures, and peri-operative management.

Main Results:

  • Ten patients with hemophilia A, B, or C (factor XI deficiency) underwent cardiac surgery.
  • Procedures included coronary artery bypass grafts and aortic valve replacement.
  • Management involved factor substitution or fresh frozen plasma; one mortality and one bleeding complication occurred.

Conclusions:

  • Major cardiac surgery can be safely performed in patients with hemophilia.
  • A multidisciplinary team approach is crucial for successful outcomes.
  • Strict postoperative monitoring is essential for managing complications.
Abstract

Keywords:
Cardiac surgeryCardiovascular diseaseFactor XI deficiencyHemophilia BHemophilia a

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