Related Experiment Video
Updated: Dec 22, 2025
![Solid-phase Synthesis of [4.4] Spirocyclic Oximes](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F58508.jpg&w=3840&q=50)
Solid-phase Synthesis of [4.4] Spirocyclic Oximes
Published on: February 6, 2019
Synthesis of polycyclic N-heterocyclic compounds via one-pot three-component cyclization strategy
Abdolali Alizadeh1, Elham Sanjari2, Atefeh Roosta2
1Department of Chemistry, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran. aalizadeh@modares.ac.ir.
Abstract:
Reported herein is an unprecedented and sequential three-component synthetic strategy for the preparation of polycyclic N-heterocyclic compounds. This synthetic protocol enabled the preparation of a series of novel nitrogen-containing pentacyclic compound under convenient conditions in excellent yields and short reaction time. The synthesized products were characterized by IR, 1H NMR, 13C NMR and mass spectra. Furthermore, the definitive structure of target compounds was confirmed by X-ray analysis.
More Related Videos
Related Concept Videos
Cycloaddition Reactions: Overview
Thermal and Photochemical Electrocyclic Reactions: Overview
Five-Membered Heterocyclic Aromatic Compounds: Overview
Cyclohexenones via Michael Addition and Aldol Condensation: The Robinson Annulation
Pericyclic Reactions: Introduction
Pericyclic reactions can be classified into three categories: electrocyclic reactions, cycloaddition reactions, and sigmatropic rearrangements. Electrocyclic reactions and sigmatropic...
Preparation of Nitriles

