[Clinico-laboratory and morphologic characteristics of the tropical splenomegaly syndrome]

A follow-up of 142 patients with the syndrome of tropical splenomegaly in Mulago Hospital in Uganda made it possible to study a clinical course, the informative value of hematological, some biochemical and immunological indices, morphological changes of liver biopsy specimens in this syndrome. Over a 10-year period 9020 autopsy records were studied for comparative assessment of a histological picture and causes of death in Mulago Hospital. The syndrome of tropical splenomegaly was diagnosed in 88 (0.98%) of them. The main diagnostic criteria were proposed for this pathology. This pathology should be denoted as the syndrome of tropical splenohepatomegaly.