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Periodontal therapy and cardiovascular risk
Marco Orlandi1, Filippo Graziani2,3, Francesco D'Aiuto1
1Periodontology Unit, UCL Eastman Dental Institute, London, UK.
Treating periodontitis may improve cardiovascular health markers. More research is needed to confirm if periodontal treatment reduces heart attacks and strokes.
Area of Science:
- Periodontology
- Cardiology
- Public Health
Background:
- Cardiovascular diseases (CVDs) are a leading global cause of death.
- Periodontitis is linked to an increased risk of CVDs.
- Previous reviews highlighted potential benefits of periodontitis treatment on cardiovascular outcomes.
Purpose of the Study:
- To review recent evidence on the impact of periodontitis treatment on cardiovascular outcomes.
- To update the understanding since the 2012 World Workshop.
- To identify gaps in current research.
Main Methods:
- Narrative review of published literature.
- Focus on randomized controlled trials (RCTs) and observational studies.
- Analysis of evidence on surrogate cardiovascular measures and hard clinical events.
Main Results:
- Newer RCTs confirm periodontal treatment positively affects surrogate cardiovascular measures.
- No RCTs have directly investigated the effect of periodontal treatment on myocardial infarction or stroke incidence.
- Observational and experimental data support a link between periodontitis treatment and improved cardiovascular markers.
Conclusions:
- Evidence supports the beneficial effect of periodontal treatment on surrogate cardiovascular measures.
- Further well-powered RCTs are needed to establish the impact of periodontal interventions on major cardiovascular events like myocardial infarction and stroke.
- Controlling traditional cardiovascular risk factors is crucial in future research.
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