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Problems and Pitfalls of Identifying Remyelination in Multiple Sclerosis
Bjoern Neumann1, Sarah Foerster1, Chao Zhao1
1Wellcome-Medical Research Council Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK.
Cell Stem Cell
|May 11, 2020
Abstract
None:
Regenerative medicines that promote remyelination in multiple sclerosis (MS) are making the transition from laboratory to clinical trials. While animal models provide the experimental flexibility to analyze mechanisms of remyelination, here we discuss the challenges in understanding where and how remyelination occurs in MS.
