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Why do parents not re-vaccinate their child for influenza? A prospective cohort study
Louise E Smith1, Richard Amlôt2, John Weinman3
1King's College London, Institute of Psychiatry, Psychology and Neuroscience, United Kingdom.
Insights
Parental concerns about severe side-effects from childhood influenza vaccination are linked to lower re-vaccination rates. Addressing parental worry may improve annual influenza immunization coverage for children.
Area of Science:
- Pediatrics
- Public Health
- Immunology
Background:
- Annual influenza vaccination rates for children in the UK are published, but data on repeat vaccination are lacking.
- Understanding factors influencing re-vaccination is crucial for maintaining herd immunity and reducing pediatric influenza burden.
Purpose of the Study:
- To identify factors associated with parents not re-vaccinating their child for influenza in the subsequent season.
- To inform strategies for improving sustained childhood influenza immunization coverage.
Main Methods:
- Prospective cohort study involving 270 children vaccinated for influenza in the 2016/17 season.
- Questionnaires collected data on vaccination, side-effects, and parental worry pre-vaccination and at 3 days and 1 month post-vaccination.
- Re-vaccination status was assessed at the end of the 2017/18 influenza season for 232 children (85.9% response rate).
Main Results:
- 17.7% (41 out of 232) of children were not re-vaccinated in the 2017/18 season.
- Parental reports of severe side-effects (p=.04) and worry about side-effects (p=.05) one month post-vaccination were associated with not re-vaccinating.
- Limited sample size impacted statistical power for definitive conclusions.
Conclusions:
- Parental perception of severe side-effects and ongoing worry are significant barriers to childhood influenza re-vaccination.
- Strategies aimed at reducing parental anxiety regarding vaccine side-effects could enhance annual influenza immunization uptake in children.
Abstract:
Child influenza vaccination rates for the UK are published annually, however there are no publicly available data on how many children are re-vaccinated the following year. This prospective cohort study aimed to identify factors associated with not re-vaccinating one's child. Participants (n = 270) completed a questionnaire before their child was vaccinated for influenza in the 2016/17 season, and follow-up questionnaires three days and one month after their child's vaccination. Re-vaccination data were collected at the end of the 2017/18 influenza season (n = 232, response rate 85.9%). Forty-one children (17.7%) were not re-vaccinated for influenza in 2017/18. Parental report of severe side-effects three days after vaccination (p = .04) and worry about side-effects one month after vaccination (p = .05) were associated with not re-vaccinating. However, the restricted sample size reduced the statistical power of these analyses. Decreasing parental worry about side-effects may help improve re-vaccination rates. Clinical trial registration: The study was registered on ClinicalTrials.gov (NCT02909855).
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