Related Experiment Video
Updated: Dec 21, 2025
Transvaginal Mesh Insertion in the Ovine Model
Published on: July 27, 2017
Efficacy and safety outcomes after genital prolapse repair by the vaginal route using the Avaulta Plus® mesh
Joana Oliveira1, Alexandra Arfi1, Anne-Sophie Boudy1
1Service de Gynécologie -Obstétrique, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris (AP-HP), UPMC, Sorbonne Université, Paris, France.
Objective(S):
With aging population, a rise in anterior wall prolapse surgery is expected. The aim of this study is to evaluate the efficacy and safety of genital prolapse repair by the vaginal route using a mixed polypropylene and porcine skin mesh (Avaulta Plus®).
Study Design:
Retrospective study conducted at Tenon University Hospital, Paris, France. We included seventy-nine women who underwent anterior wall prolapse repair using Avaulta Plus® mesh by the transobturator route for genital prolapse ≥ stage II from September 2008 to December 2017. Pre- and postoperative pelvic organ prolapse classification, functional symptoms, quality of life scores were evaluated, and complications were recorded.
Results:
The anatomical success rate for anterior wall prolapse was 97 %. The postoperative complication rate was 29.1 % among which the mesh exposure rate was 7.6 %. Pelvic symptoms such as vaginal discomfort and pelvic heaviness were significantly improved (p < 0.01). Voiding dysfunction were significantly improved (p < 0.01). A significant improvement in the PFDI-20 score (p < 0.01) and PFIQ-7 score (p < 0.01) was observed. After 3 years of follow-up, the recurrence rate was 12 %.
Conclusion(S):
Prolapse repair using the Avaulta Plus® mesh is effective and results in a significant improvement in quality of life. The complication rate, including mesh exposure, is acceptable.
