The special vulnerability of children

Ruth A Etzel1

  • 1Milken Institute School of Public Health, The George Washington University, Washington, DC, USA.

Summary

Children

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Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
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Relationship with Other Adult Family Members and Siblings01:29

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