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Updated: Dec 21, 2025

Bloodless Laparoscopic Partial Splenectomy Assisted by Bipolar Radiofrequency Excision Hemostatic Device
Published on: November 4, 2022
How I approach hereditary hemolytic anemia and splenectomy
Jennifer A Rothman1, Jenny L Stevens2,3, Fabienne L Gray2,3
1Division of Pediatric Hematology/Oncology, Duke University, Durham, North Carolina.
Abstract:
Hereditary hemolytic anemias (HHA) are a heterogeneous group of anemias associated with decreased red cell survival. While there can be clinical benefit of splenectomy in many cases, splenectomy is not appropriate for all types of HHA. Additionally, there are significant risks during and following splenectomy including surgical risks, postsplenectomy sepsis, and thrombotic complications. This review discusses the diagnostic approach to HHA as well as the role of splenectomy in the management. Surgical approaches and outcomes for total and partial splenectomy are discussed.
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