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Updated: Dec 21, 2025

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
Published on: March 3, 2023
[An 84-year-old man with an ulcer on his ankle]
Nicole van Berkum-Zandkamp1,2, Ronald H Houwing1, Rosanne Sanders-Koers1
1Deventer Ziekenhuis, afd. Dermatologie, Deventer.
Abstract:
Hydroxycarbamide is a cytotoxic drug that is used in haematological cancers. On long-term use (2-15 years) of 1500-2000 mg a day, there is a 9% risk of developing ulcers. This patient's ulcer was painful, of punched out aspect, with a necrotic base and swollen wound edges. Upon discontinuation of hydroxycarbamide, the wound healed within 2 months.
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