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Updated: Dec 21, 2025

Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma
Published on: September 20, 2024
[Synchronous Thymic Carcinoma and Primary Lung Cancer]
Masafumi Tamaki1, Koichiro Kenzaki, Kazumasa Miura
1Department of Surgery, Kagawa Prefectural Shiratori Hospital, Higashikagawa, Japan.
Abstract:
A 79-year-old woman visited a local doctor with a chief complaint of cough. A computed tomography (CT) scan revealed an anterior mediastinal tumor and 20 mm sized ground-glass nodule (GGN) in the right upper lobe. Bronchoscopy was performed, but no definitive diagnosis was made for GGN and follow-up observation was made with an image. The anterior mediastinal tumor was a solid tumor of 50 mm in size, and invasive thymoma was suspected. A total thymectomy with pericardial partial resection was performed through a median sternotomy. Histopathological diagnosis was squamous cell carcinoma, and no pericardial infiltration was observed. On the other hand, GGN of the right upper lobe during follow-up increased in size and thoracoscopic surgery was performed 3 months after surgery for thymic carcinoma. Adenocarcinoma was diagnosed by rapid diagnosis and the upper lobectomy with lymph node dissection were conducted. No signs of recurrence have been observed for 5 years after operation.
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