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Single Port Donor Nephrectomy
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Severe hyponatremia after donor nephrectomy.

Ihab A Ibrahim1, Ehab A Hassan1, Tariq Z Ali1

  • 1Department of Kidney Transplantation, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.

Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
|May 13, 2020
PubMed
Summary
This summary is machine-generated.

Severe hyponatremia after kidney donation can occur. This case highlights the importance of diagnosing hypocortisolism over SIADH for effective treatment and patient recovery.

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Area of Science:

  • Nephrology
  • Endocrinology
  • Surgical Complications

Background:

  • Living kidney donation is generally safe but carries risks of complications.
  • Hyponatremia, a common electrolyte imbalance, increases patient morbidity and mortality.
  • Accurate diagnosis of hyponatremia's cause is crucial for management and prognosis.

Observation:

  • A patient developed severe hyponatremia post-left donor nephrectomy.
  • Physical exam suggested mild hypovolemia.
  • Lab results mimicked SIADH but showed a blunted response to Synacthen.

Findings:

  • The patient's hyponatremia was successfully treated with hydrocortisone.
  • The condition was attributed to hypocortisolism, not SIADH.
  • This case presents an unusual instance of hyponatremia following donor nephrectomy.

Implications:

  • Distinguishing adrenal insufficiency from SIADH is vital for treating severe hyponatremia.
  • Hypocortisolism may be an underrecognized cause of hyponatremia after nephrectomy.
  • Early diagnosis and treatment of hypocortisolism can improve patient outcomes.