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Stroke in the Blida region (Algeria) in 2018: Incidence and mortality according to a population-based register
Insights
This study established stroke incidence and mortality in Blida, Algeria, using a population-based register. Results highlight a significant burden of disease, with higher incidence and mortality rates in men.
Area of Science:
- Neurology
- Epidemiology
- Public Health
Background:
- Stroke represents a significant global health challenge.
- Accurate epidemiological data is crucial for understanding stroke burden and planning interventions.
Purpose of the Study:
- To establish incidence and mortality data for stroke in the Blida region, Algeria, for 2018.
- To quantify stroke risk, occurrence, and death rates using a population-based register.
Main Methods:
- Utilized World Health Organization criteria for stroke definition.
- Required cerebral imaging for confirmation and mechanism determination (hemorrhagic/ischemic).
- Targeted inhabitants of Blida aged 25 and over; calculated incidence, mortality rates, relative risk (RR), and standardized mortality ratio (SMR).
Main Results:
- Recorded 828 strokes: 85.1% ischemic, 13.5% hemorrhagic.
- Overall stroke incidence rate was 130.3/100,000 (standardized: 138.1/100,000).
- Men showed significantly higher incidence (143.6/100,000) and mortality (34.5/100,000) than women; 28-day case-fatality rate was 22.1%.
Conclusions:
- A stroke register in Blida effectively quantified disease risk and burden.
- Findings underscore the public health impact of stroke in the region.
- Data can inform targeted prevention and management strategies.
Objective:
Establishing the incidence and mortality data for stroke in the Blida region (Algeria) for 2018, through the setting up of a population-based register, was the objective of this study.
Methods:
The World Health Organization criteria were used to define the stroke. Cerebral imaging was required to confirm stroke and its hemorrhagic or ischemic mechanism. The target population of the study was inhabitants of the region (wilaya) of Blida (Algeria) aged 25 and over. The ratios of overall incidence and mortality rates and age-specific stroke rates were considered to be relative risk (RR). The Standardized Mortality Ratio (SMR) was the ratio of standardized rates.
Results:
A total of 828 stroke were reported, 85.1% ischemic and 13.5% hemorrhagic. The first-ever strokes constituted 70.5% of the strokes for which the occurrence was documented. The overall incidence rate of stroke for 2018, regardless of mechanism and occurrence, was estimated at 130.3/100000. The corresponding standardized rate for age was 138.1/100000. The incidence rate among men (143.6/100000) was significantly higher than that of women (116.9/100000): RR = 0.81 (95% CI: 0.71; 0.93). The median age of onset of stroke was 70 years. The case-fatality rate at 28 days was 22.1%. The overall mortality rate was 28.8/100000 while the corresponding standardized rate was 29.9/100000. The standardized mortality rate for men (34.5/100000) was significantly higher than for women (25.3/100000): SMR = 0.73 (95% CI: 0.54; 0.99).
Conclusion:
The setting up of a register for stroke in the Blida region has made it possible to quantify the risk of stroke, occurrence and death, and to alert about the burden of disease attributable to this health problem.
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