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AIDS-Related Mycoses: Updated Progress and Future Priorities

J Claire Hoving1, Gordon D Brown2, Beatriz L Gómez3

  • 1AFGrica Medical Mycology Research Unit, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, South Africa; Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, South Africa; MRC Centre for Medical Mycology at the University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter, UK.

Trends in Microbiology
|May 13, 2020
PubMed

Insights

Serious fungal infections remain a major threat for people with HIV, causing many deaths. A recent workshop identified key actions to advance the fight against these AIDS-related mycoses.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • HIV/AIDS Research

Background:

  • Serious fungal infections are a significant cause of mortality in individuals with HIV/AIDS.
  • These infections are the second leading cause of death in this population, surpassed only by tuberculosis.
  • Advances in understanding and managing AIDS-related mycoses are crucial for improving patient outcomes.

Purpose of the Study:

  • To review and update progress in the field of AIDS-related mycoses over the past three years.
  • To identify critical challenges and future research directions.
  • To establish key action points for the advancement of the field.

Main Methods:

  • The content is based on discussions and findings from the third AIDS-related mycoses workshop.
  • Expert consensus and review of recent scientific advancements formed the basis of the update.
  • Identification of six key action points through collaborative discussion.

Main Results:

  • Significant progress has been made in understanding AIDS-related mycoses.
  • Six key action points were identified to guide future research and clinical practice.
  • The workshop highlighted the ongoing importance of addressing fungal infections in people living with HIV.

Conclusions:

  • Continued research and strategic action are necessary to combat serious fungal infections in people living with HIV.
  • The identified action points provide a roadmap for future efforts in the field of AIDS-related mycoses.
  • Addressing these fungal infections is critical to reducing mortality in the HIV-positive population.
Keywords:
AIDSadvanced HIVdiagnosticsfungal infectiontreatment

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