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Genetic Alterations Impact Immune Microenvironment Interactions in Follicular Lymphoma
Carsten Riether1, Adrian F Ochsenbein1
1Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland.
Cancer Cell
|May 13, 2020
Abstract:
Interactions between germinal center B cells and immune cells in the microenvironment can play integral roles in transformation and growth of follicular lymphoma (FL). Three recent studies, two in this issue of Cancer Cell and one in Cell Reports, elucidate how genetic alterations in CTSS and EZH2 impact these interactions, with implications for FL immunotherapy.

