Inflammation, diet, and type 2 diabetes: a mini-review
Simin Jafaripour1, Sima Sedighi2, Mohammad Hassan Jokar2
1Department of Medical Genetics, School of Medicine, Mashhad University of Medical Sciences , Mashhad, Iran.
Abstract:
Inflammation is a common feature of type 2 diabetes (T2D). Inflammatory cytokines increase in patients with type 2 diabetes, metabolic syndrome, and heart disease. Various types of cells can produce inflammatory cytokines and then release them into the bloodstream, where their complex interactions with target tissues raise a tissue-specific immune response. This review focused on C-reactive protein (CRP), tumor necrosis factor (TNF)-α as an inflammatory cytokine, and adiponectin produced by adipose tissues. Despite the major role of cytokines in the development of T2D, further studies are required to investigate the possible effects of the macronutrient composition of diet on these cytokines.
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