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Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
Published on: January 26, 2024
Cardiovascular effects of preeclampsia
Smitha Neerukonda1, Farnoosh Shariati2, Taylor Hart1
1John Ochsner Heart and Vascular Institute.
Purpose Of Review:
Preeclampsia complicates 3-5% of first and 15% of subsequent pregnancies. This study reviews the evidence of increase cardiovascular risk in these women.
Recent Findings:
Women with preeclampsia are at two-fold higher risk for development of coronary artery disease, stroke and death, and four-fold increased risk of heart failure. Preeclampsia developed in early part of pregnancy confers greater risk than later in pregnancy. Common factors that predispose women to preeclampsia also confer high risk for developing cardiovascular disease include obesity, metabolic abnormalities, dyslipidaemia, insulin resistance, heightened inflammatory responses, hypercoagulable states and endothelia dysfunction.
Summary:
Patients with preeclampsia should be screened at regular intervals by a preventive cardiologist and treated accordingly.
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