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Updated: Jul 20, 2026

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Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
Published on: March 20, 2015
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Dual-polarized highly sensitive surface-plasmon-resonance-based chemical and biomolecular sensor
Applied Optics
|May 14, 2020
Summary
A novel photonic crystal fiber (PCF) with elliptical air holes significantly enhances surface plasmon resonance (SPR) sensor performance. This design offers superior sensitivity and birefringence for advanced chemical and biomolecular detection.
Area of Science:
- Optoelectronics and Photonics
- Nanotechnology
- Chemical Sensing
Background:
- Surface Plasmon Resonance (SPR) based Photonic Crystal Fiber (PCF) sensors are crucial for detecting chemical and biomolecular analytes.
- Optimizing PCF structure is key to improving SPR sensor performance parameters like sensitivity and birefringence.
Purpose of the Study:
- To propose and investigate a novel circular-shaped PCF with elliptical air holes for enhanced SPR sensing.
- To compare the performance of PCF designs with elliptical, circular, and rectangular air holes.
- To achieve high sensitivity, resolution, and birefringence for dual-polarized operation.
Main Methods:
- Utilized the finite element method (FEM) for theoretical investigation.
- Employed COMSOL Multiphysics 5.3a software for numerical simulations.
- Analyzed sensor performance across the optical spectrum from 0.59 to 1.05 µm for analytes with refractive indices (RI) from 1.33 to 1.40.
Main Results:
- The proposed elliptical air hole PCF design demonstrated significantly improved performance compared to circular and rectangular designs.
- Achieved a maximum confinement loss of 340 dB/cm.
- Reported wavelength sensitivity of 13,000 nm/RIU and amplitude sensitivity of 1189.46 RIU-1.
- Obtained a sensor resolution of 7.69 × 10-6.
- Reached a maximum birefringence of 2.8 × 10-3, the highest reported for a PCF-SPR sensor, enabling dual-polarized operation.
Conclusions:
- The designed elliptical air hole PCF structure offers superior performance for SPR-based sensing applications.
- The high birefringence and sensitivity make it suitable for advanced chemical and biomolecular detection.
- This PCF design represents a significant advancement in the field of optical sensing.

