Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clearance Models: Compartment Models01:25

Clearance Models: Compartment Models

255
Clearance measures drug elimination from the central compartment, including plasma and highly perfused organs like kidneys and liver. Its calculation varies depending on pharmacokinetic models and administration routes. The one-compartment model, for instance, portrays the pharmacokinetics of polar drugs such as aminoglycoside antibiotics administered intravenously and readily excreted in urine. In this case, clearance is influenced by the terminal rate constant (λz) and the total volume...
255
Clearance Models: Physiological Models01:09

Clearance Models: Physiological Models

237
Drug clearance is a critical pharmacokinetic process involving the irreversible removal of drugs from the body through various organs over a specified time period. Physiological models are indispensable in determining organ-specific clearance, defined by the proportion of the drug eliminated per unit of time from the organ's blood volume.
The organ's clearance rate depends on the blood flow to the organ and the extraction ratio (E). The extraction ratio describes the organ's...
237
Composite Bodies00:55

Composite Bodies

1.3K
A composite body is a body made up of multiple parts, connected to form a larger, unified object. Each part has its own weight and center of gravity, which must be considered to determine the center of gravity of the composite body. In cases where the density or specific weight is constant, the center of gravity coincides with the centroid.
Composite bodies have widespread applications in mechanical engineering, from automobiles to aircraft to rockets. For example, an automobile wheel comprises...
1.3K
Typical Model Studies01:30

Typical Model Studies

556
Fluid mechanics model studies often utilize scaled-down systems to predict fluid behavior in full-scale environments, such as river flows, dam spillways, and structures interacting with open surfaces. Maintaining Froude number similarity in river models is crucial, as it replicates surface flow features like wave patterns and velocities.
556
Design Consideration01:22

Design Consideration

474
Designing a structure involves a series of considerations, primarily the material's ultimate strength, calculated through tests that measure changes under increased force until the material reaches its breaking point or limit. The ultimate load, where the material breaks, is divided by its original cross-sectional area, resulting in the ultimate normal stress or strength. The ultimate shearing stress is another significant factor taken into account.
The factor of safety is another key...
474
Simplification of a Force and Couple System I01:18

Simplification of a Force and Couple System I

867
The concept of reducing a system of forces and couple moments to an equivalent system is essential in simplifying the analysis of rigid bodies. This reduction allows for more straightforward computation and understanding of the external effects produced by the system. In particular, systems with an equivalent resultant force and a resultant couple moment having perpendicular lines of action can be further reduced to a single equivalent resultant force acting along a new line of action. There...
867

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Model order reduction techniques to identify submarining risk in a simplified human body model.

Computer methods in biomechanics and biomedical engineering·2023
Same author

B-cell activating factor BAFF as a novel alert marker for the immunological risk stratification after kidney transplantation.

Immunologic research·2021
Same author

Observational study of the long-term impact of donor-site sequelae after head and neck reconstruction by free anterolateral thigh flap.

European annals of otorhinolaryngology, head and neck diseases·2021
Same author

Assessment of swallowing function after circumferential pharyngolaryngectomy. A multicenter study by the GETTEC group.

European annals of otorhinolaryngology, head and neck diseases·2018
Same author

Anti-HLA alloantibodies of the IgA isotype in re-transplant candidates part II: Correlation with graft survival.

International journal of immunogenetics·2018
Same author

How much do we know about the frequency of hybridisation and polyploidy in the Mediterranean region?

Plant biology (Stuttgart, Germany)·2017
Same journal

Analysis of typical cases of medical infusion pump metering acceptance in nursing scenarios.

Computer methods in biomechanics and biomedical engineering·2026
Same journal

Investigation of biomechanical effect of inverted orthotic insoles on flexible flatfeet.

Computer methods in biomechanics and biomedical engineering·2026
Same journal

FeuNet: cross-user gesture recognition and fingertip force estimation network based on feature enhancement and U-Net.

Computer methods in biomechanics and biomedical engineering·2026
Same journal

Both chronological age and individual differences in aging are the two indispensable components for predicting biological age.

Computer methods in biomechanics and biomedical engineering·2026
Same journal

Effects of restraint tether devices on pilots' neck injuries under arrested landing conditions.

Computer methods in biomechanics and biomedical engineering·2026
Same journal

Advancing cardiac health assessment using deep convolutional neural networks for ECG image analysis.

Computer methods in biomechanics and biomedical engineering·2026
See all related articles

Related Experiment Video

Updated: Dec 21, 2025

Structural Design and Manufacturing of a Cruiser Class Solar Vehicle
14:57

Structural Design and Manufacturing of a Cruiser Class Solar Vehicle

Published on: January 30, 2019

14.3K

Positioning human body models for crashworthiness using model order reduction.

G Bacquaert1,2, C Bach1,3, D Draper1,4

  • 1BMW AG, Research and Innovation Centre, Munich, Germany.

Computer Methods in Biomechanics and Biomedical Engineering
|May 14, 2020
PubMed
Summary
This summary is machine-generated.

This study introduces a novel method to quickly position human body models (HBMs) using dimensionality reduction. The technique accelerates simulations for improved safety analysis.

Keywords:
Human body modelsautomotivecrash simulationdimensionality reductionseating positions

More Related Videos

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion
09:32

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion

Published on: April 11, 2018

10.1K
A Test Bed to Examine Helmet Fit and Retention and Biomechanical Measures of Head and Neck Injury in Simulated Impact
07:30

A Test Bed to Examine Helmet Fit and Retention and Biomechanical Measures of Head and Neck Injury in Simulated Impact

Published on: September 21, 2017

9.2K

Related Experiment Videos

Last Updated: Dec 21, 2025

Structural Design and Manufacturing of a Cruiser Class Solar Vehicle
14:57

Structural Design and Manufacturing of a Cruiser Class Solar Vehicle

Published on: January 30, 2019

14.3K
Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion
09:32

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion

Published on: April 11, 2018

10.1K
A Test Bed to Examine Helmet Fit and Retention and Biomechanical Measures of Head and Neck Injury in Simulated Impact
07:30

A Test Bed to Examine Helmet Fit and Retention and Biomechanical Measures of Head and Neck Injury in Simulated Impact

Published on: September 21, 2017

9.2K

Area of Science:

  • Biomechanics
  • Computational modeling
  • Human body simulation

Background:

  • Accurate human body model positioning is crucial for safety simulations.
  • Existing methods can be computationally intensive, limiting simulation speed.
  • The Total Human Model for Safety (THUMS) requires efficient positioning for various scenarios.

Purpose of the Study:

  • To present a new technique for accelerating the positioning of human body models (HBMs).
  • To reduce the dimensionality of precomputed simulation data for faster computations.
  • To enable efficient HBM positioning for complex scenarios like reclined seating.

Main Methods:

  • Dimensionality reduction of a precomputed simulation database.
  • Computation of important subspace deformation modes to approximate model movements.
  • Solving a convex optimization problem to achieve user-defined optimal HBM positioning.

Main Results:

  • The proposed method successfully accelerates the positioning of human body models.
  • Demonstrated application to a reclined seating position using the THUMS v5 model.
  • Achieved optimal HBM positioning based on user specifications.

Conclusions:

  • The new technique significantly speeds up HBM positioning.
  • This method enhances the efficiency of safety analysis simulations.
  • Applicable to various human body models and complex postures.