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COVID-19: Updated Data and its Relation to the Cardiovascular System
1Programa de Pós-Graduação em Cardiologia e Ciências Cardiovasculares, Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS - Brasil.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19, a pandemic illness. COVID-19 may worsen underlying cardiovascular conditions and impact patients using ACE inhibitors, necessitating careful risk-benefit assessment.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- The emergence of SARS-CoV-2 has led to a global pandemic (COVID-19).
- COVID-19 presents with respiratory symptoms and is associated with cardiac complications.
- Patients with pre-existing cardiovascular conditions or on specific medications may face increased risks.
Purpose of the Study:
- To explore the relationship between COVID-19 and cardiovascular health.
- To investigate the potential impact of ACE inhibitors and ARBs on COVID-19 progression.
- To inform healthcare professionals about managing COVID-19 in cardiac patients.
Main Methods:
- Literature review and synthesis of current evidence regarding COVID-19 and cardiovascular disease.
- Analysis of the role of ACE2 receptors in viral entry.
- Discussion of clinical implications for patients with hypertension and diabetes.
Main Results:
- A significant number of hospitalized COVID-19 patients have cardiovascular or cerebrovascular diseases.
- Systemic inflammation and immune dysregulation may link COVID-19 to cardiac damage.
- No current evidence supports discontinuing ACE inhibitors or ARBs due to COVID-19 risk.
Conclusions:
- COVID-19 can exacerbate underlying cardiovascular conditions.
- The use of ACE inhibitors and ARBs requires careful consideration of risks and benefits in the context of COVID-19.
- Cardiologists and healthcare providers must remain vigilant and protect themselves during the pandemic.
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