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Severe Coronavirus Disease-2019 in Children and Young Adults in the Washington, DC, Metropolitan Region

Roberta L DeBiasi1, Xiaoyan Song2, Meghan Delaney3

  • 1Division of Pediatric Infectious Diseases, Children's National Hospital, Washington, DC; Department of Pediatrics, The George Washington University School of Medicine and Health Sciences, Washington, DC; Department of Microbiology, Immunology and Tropical Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC.

The Journal of Pediatrics
|May 15, 2020
PubMed

Insights

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) can cause severe illness in children and young adults. Adolescents and young adults over 15 were more likely to be critically ill.

Area of Science:

  • Pediatric infectious diseases
  • Virology
  • Public health

Background:

  • Limited data exist on severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) disease severity in pediatric populations.
  • Understanding risk factors for severe COVID-19 in children is crucial for public health strategies.

Observation:

  • A study analyzed 177 children and young adults infected with SARS-CoV-2.
  • 44 patients required hospitalization, and 9 were critically ill.

Findings:

  • Children under 1 year and young adults over 15 were over-represented in the hospitalized group.
  • Adolescents and young adults (over 15) showed a statistically significant over-representation in the critically ill cohort (P = .02).

Implications:

  • These findings highlight specific age groups within the pediatric population at higher risk for severe COVID-19.
  • This information can inform targeted clinical monitoring and resource allocation for pediatric severe acute respiratory syndrome coronavirus-2 cases.

Keywords:
COVID-19SARS-CoV-2critical carehospitalizationpediatric

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