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Related Concept Videos

Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Other Pulmonary Disorders01:17

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Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
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Pulmonary Tuberculosis I01:29

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
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Diffuse large B-cell lymphoma presenting with cavitary lung disease.

Yukiko Hibino1, Ryosuke Imai2, Torahiko Jinta2

  • 1Department of Internal Medicine St. Luke's International Hospital Tokyo Japan.

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|May 15, 2020
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Summary
This summary is machine-generated.

Diffuse large B-cell lymphoma (DLBCL) presenting as cavitary lung disease is rare. This case highlights the importance of considering DLBCL in patients with cavitary lung lesions and splenic masses.

Keywords:
Cavitary lung diseasediffuse large B‐cell lymphoma

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Area of Science:

  • Oncology
  • Pulmonology
  • Pathology

Background:

  • Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma.
  • Cavitary lung disease can be challenging to diagnose, with differential diagnoses including malignancy, granulomatous disease, and infection.
  • Imaging findings alone are often insufficient to differentiate these conditions.

Observation:

  • A patient presented with cavitary lung disease and a splenic mass.
  • The clinical presentation mimicked primary lung cancer or infectious/granulomatous processes.

Findings:

  • Transbronchial biopsy confirmed DLBCL as the cause of cavitary lung disease.
  • The splenic mass was also identified as DLBCL metastasis.

Implications:

  • DLBCL should be included in the differential diagnosis for patients with cavitary lung disease.
  • Rare metastatic patterns of DLBCL, such as splenic involvement, should be recognized.
  • Early consideration of DLBCL can lead to timely diagnosis and treatment.