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Updated: Dec 21, 2025
Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
Published on: January 26, 2024
Fetal gender, serum human chorionic gonadotropin, and testosterone in women with preeclampsia
Zakia M Ibrahim1, Eman A Kishk1, Mahmoud S Elzamlout1
1Department of Obstetrics and Gynecology, Faculty of Medicine, Suez Canal University , Ismailia, Egypt.
Objectives:
Evaluation of the association between fetal gender, serum beta-human chorionic gonadotropin, and serum testosterone, and preeclampsia.
Methods:
Case-control study conducted at the Obstetrics and Gynecology Department. 120 patients divided into study group (patients with preeclampsia subdivided into mild and severe) and control group (normotensive women).
Interventions:
Fetal gender was determined. Serum testosterone and HCG levels were estimated at 32 weeks or at the time of diagnosis of preeclampsia (study group) or recruitment (control group).
Results:
Positive association between the male gender of the fetus and preeclampsia. Increased HCG and Testosterone were associated with developing preeclampsia.
Conclusion:
The mechanism of preeclampsia could be androgen-mediated. There is a significant correlation between serum HCG and testosterone and preeclampsia.
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