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Updated: Dec 21, 2025
Author Spotlight: Unveiling the Pathway Linking Obesity to Autoimmune Inflammation in Multiple Sclerosis
Published on: February 23, 2024
Dietary factors in experimental autoimmune encephalomyelitis and multiple sclerosis: A comprehensive review
Claire Valburg1, Anup Sonti1, Joel Nh Stern2
1Department of Neurology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, NY, USA.
Background:
Dietary intervention in multiple sclerosis carries potential therapeutic implications. While studies utilizing animal models of multiple sclerosis (MS) have demonstrated intriguing findings, well-designed clinical trials are few in number.
Objective:
The objective of this study is to review the animal model and clinical literature regarding dietary factors in experimental autoimmune encephalitis (EAE) and MS.
Methods:
This manuscript provides a comprehensive review of current animal model and clinical knowledge related to dietary factors in MS.
Results:
While there is currently little data for any specific diet in MS, there is growing evidence that certain dietary factors may influence the disease.
Conclusions:
Definitive information regarding dietary factors as a modifiable risk factor in MS will require larger randomized clinical trials.
