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Updated: Dec 21, 2025

Heterokaryon Technique for Analysis of Cell Type-specific Localization
Published on: March 11, 2011
A neural mechanism of nuclear receptor expression and regionalization
1Department of Biology, University of Tirana, Tirana, Albania.
Abstract:
Spatially restricted expression of genes by global circulating inducers (hormones, secreted proteins, growth factors, neuromodulators, etc.) was a prerequisite for the evolution of animals. Far from a random occurrence, it is a systematically occurring, certain event, implying that specific information is invested for it to happen. In this minireview, we show for the first time that the expression and regionalization takes place at the level of receptors via a neural mechanism and make an attempt to reconstruct the causal chain from neural signaling to expression of nuclear receptors.
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