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Updated: Dec 21, 2025

Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo
Published on: July 1, 2013
Tissue level implants in healthy versus medically compromised patients: a cohort comparative study.
Vincenzo Marchio1, Giacomo Derchi2, Chiara Cinquini2
1Unit of Stomatology and Oral Surgery, Department of Surgical, Medical, Molecular and Critical Needs Pathologies, University Hospital of Pisa, University of Pisa, Pisa Italy - marchio.vincenzo@hotmail.it.
Dental implants in medically compromised patients show similar survival and success rates to those in healthy patients after one year. Soft tissue response also showed no significant differences between groups.
Area of Science:
- Dental Implantology
- Oral Surgery
- Periodontology
Background:
- Medically compromised patients often present with conditions impacting oral health.
- Dental implants in these patients have demonstrated predictable outcomes and high survival rates.
- This study compares implant outcomes in healthy versus medically compromised individuals.
Purpose of the Study:
- To compare implant survival and success rates in healthy versus medically compromised patients.
- To evaluate soft tissue response to tissue-level implants in both groups.
- To assess marginal bone level changes after one year.
Main Methods:
- Seventy-two patients (36 healthy, 36 medically compromised) received one tissue-level implant.
- Medically compromised patients had conditions like cardiovascular disease, diabetes, or osteoporosis.
- Implant survival, success, soft tissue response, and marginal bone levels were measured at baseline and 1-year follow-up.
Main Results:
- Overall, 72 implants were placed with a high survival rate.
- No statistically significant differences in implant success or survival rates were found between healthy and medically compromised patients.
- While healthy patients experienced a slight mean loss of keratinized tissue, medically compromised patients showed a mean gain.
Conclusions:
- Tissue-level implants demonstrate comparable short-term (1-year) success, failure, and survival rates in both healthy and medically compromised individuals.
- No significant differences in marginal bone level were observed between the groups.
- Soft tissue response varied slightly, with a gain in medically compromised patients and a loss in healthy patients.
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