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Updated: Dec 21, 2025

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
Published on: March 21, 2013
Orthostatic hypotension: clinical review and case study
Rachael Bailey1, Gerri Mortimore2
1Trainee Advanced Clinical Practitioner, Department of Health and Social Care, University of Derby.
Transient loss of consciousness (TLOC) is common in emergency departments, often misdiagnosed. This article highlights orthostatic hypotension as a critical diagnosis to prevent mortality and improve patient outcomes.
Area of Science:
- Medical Sciences
- Clinical Medicine
- Emergency Medicine
Background:
- Transient loss of consciousness (TLOC) is a frequent emergency department presentation, with over 90% attributed to seizures or syncope.
- Incorrect epilepsy diagnoses in England and Wales cost the NHS up to £189 million annually.
- Accurate TLOC diagnosis is crucial for appropriate management and identifying mortality risks.
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