An Electrochemical Non-Enzymatic Glucose Sensor Based on Ultrathin PdAg Single-Crystalline Nanowires

Electrochemical non-enzymatic sensors have great potential for prompt and efficient detection of glucose. Herein, a novel, highly efficient electrochemical non-enzymatic glucose sensor is reported that is based on ultrathin PdAg single-crystalline nanowires (NWs). Ultrathin PdAg NWs are fabricated by a facile one-pot aqueous synthesis through an in situ growth strategy with an amphiphilic surfactant as the template. A comparison of the activities of PdAg NWs with different compositional ratios and nanostructures shows that ultrathin Pd₂ Ag₁ NWs hold the best performance toward electrochemical detection of glucose with an operable sensitivity of 11.6 μA mM^-1  cm^-2 and a linear response range of 0.1-8 mM. Structural and compositional features of the Pd₂ Ag₁ NWs allow an excellent selectivity, rapid response, and good long-term stability for electrochemical glucose sensor. This work thus provides a new possibility for the rational design and synthesis of noble-metal-based nanomaterials for non-enzymatic sensors.